منابع مشابه
Pyridostigmine, working and toxicity on platelet.
I read the recent publication by Leong et al on the effect of pyridostigmine or Mestinon on human platelet aggregation with a great interest. In medicine, pyridostigmine has been investigated for its effect on biochemical and hematological parameters. Indeed, such effects have already been studied in animal models. Somani et al reported on signifi cant change due to receipt of pyridostigmine in...
متن کاملBradycardia produced by pyridostigmine and physostigmine.
PURPOSE The bradycardia produced by pyridostigmine and physostigmine in an animal model of acute cardiac denervation was examined according to its relation to cholinesterase inhibition and sensitivity to block by cholinergic receptor antagonists. METHODS Cats were anaesthetised, vagotomised and propranolol-treated. Heart rate was continuously recorded. Erythrocyte cholinesterase activity of a...
متن کاملPyridostigmine treatment trial in neurogenic orthostatic hypotension.
BACKGROUND Midodrine hydrochloride is the only drug demonstrated in a placebo-controlled treatment trial to improve orthostatic hypotension (OH) but it significantly worsens supine hypertension. By enhancing ganglionic transmission, pyridostigmine bromide can potentially ameliorate OH without worsening supine hypertension. OBJECTIVE To evaluate the efficacy of a single 60-mg dose of pyridosti...
متن کاملEffect of pretreatment with oral pyridostigmine.
CORRESPONDENCE MANAGEMENT OF CARBOXYHAEMOGLOBINAEMIA Sir,—Drs Vegfors and Lennmarken have demonstrated usefully how easy it is to be misled in the management of carbon monoxide poisoning [1]. Their case deserves further comment. Unfortunately, there is little information on the mechanism of cellular toxicity of carbon monoxide. Carbon monoxide binds to haem-containing enzymes such as cytochrome...
متن کاملPersistently exaggerated startle responses in rats treated with pyridostigmine bromide.
Troops in the Persian Gulf War have registered complaints consistent with CNS dysfunction that emerged after returning from the Gulf. A common experience among Persian Gulf War veterans was exposure to pyridostigmine bromide (PB) for prophylaxis against nerve gas exposure. To determine whether PB causes emergent CNS dysfunction, Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rats were given PB for ...
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ژورنال
عنوان ژورنال: Reactions Weekly
سال: 2021
ISSN: ['1179-2051', '0114-9954']
DOI: https://doi.org/10.1007/s40278-021-95972-y